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長庚大學 光電工程研究所
周晟 教授
周 晟

Citizen of Taiwan, Republic of China, Birth place: ChengDu, Sichuan, China

- Surface Plasmon Biosensors & Imaging Ellipsometry

- Near Infrared Spectroscopy & Heterodyne Polarimetry

- Two-frequency Laser Scanning Confocal Microscopy

1978.12       Biomedical Optics, University of Arizona, Ph.D.
1975.08       Optics, University of Rochester, M.S.
1969.02       Physics, Chung Cheng Institute of Technology, B.S.

1990~2009 Professor, Department of Biomedical Imaging and Radiological Sciences (BIRS), National Yang-Ming University, Taipei, Taiwan

2009~    Professor, Graduate Institute of Electro-Optical Engineering, Chang Gung University, Taoyuan, Taiwan

長庚大學教授 ( 2009 -     )
陽明大學教授 ( 1990 - 2009 )

SCI Journals:

1.    C. Chou, H. M. Tsai, K. Y. Liao, L. D. Chou, P. H. Huang, “Optical activity measurement of quartz crystal using a balanced optical heterodyne interferometer”  Applied Optics 45, 3733-3739, (2006).

2.    H. F. Chang, C. Chou, H. K. Teng, H. T. Wu, H. F. Yau, “The use of polarized modulation and amplitude-sensitive optical heterodyne interferometer for linear birefringence parameters measurements”

3.    Optics Communications 260, 420-426, (2006).C. Chou, H. K. Teng, C. C. Tsai, L. P. Yu, “Balanced detector interferometric ellipsometry,” Journal of The Optical Society of America A 23, 2871-2879, (2006).

4.    C. Chou, H.T. Wu, Y.C. Huang, Y.L. Chen, W.C. Kuo, “The characteristics of a paired surface plasma waves heterodyne biosensor,” Optics Express 14, 4307-4315, (2006).

5.    W. C. Kuo, N. K. Chou, C. Chou, C. M. Lai, H. J. Huang, S. S. Wang, J. J. Shyu, “Polarization-sensitive optical coherence tomography for imaging human atherosclerosis,” Applied Optics 46, 2520-2527, (2007).

6.    C. Chou, H. Y. Hsu, H. T. Wu, K. Y. Tseng , A. Chiou, C. J. Yu, , Z. Y. Lee, T. S. Chan, “Fiber-optic biosensor for detection of C- reative protein and monitor of protein binding kinetics,” Journal of Biomedical Optics 12, 024035, (2007).

7.    C. C. Tsai, H. C. Wei, C. H. Hsieh, L. P. Yu, C. R. Yu, H. S. Huang, C. Chou, “Characterization of a nematic PALC at large oblique incidence angles,” Optics Express 15, 10381-10389, (2007).

8.    C. H. Hsieh, C. C. Tsai, H. C. Wei, L. P. Yu, J. S. Wu, C. Chou, “Determination of retardation parameters of multiple-order waveplate using a phase sensitive heterodyne ellipsometer,” Applied Optics 46, 5944-5950, (2007).

9.    C. Chou, K. H. Chiang, K. Y. Liao, Y. F. Chang, C. E. Lin, “Polarized photon-pairs heterodyne polarimetry for ultrasensitive optical activity detection of a chiral medium,” Journal of Physical Chemistry B 111, 9919-9922, (2007).

10. B. Y. Hsieh, Y. F. Chang, M. Y. Ng, W. C. Liu, C. H. Lin, H. T. Wu, C. Chou, “Localized surface plasmon coupled fluorescence fiber-optic biosensor with gold nanoparticles,” Analytical Chemistry 79, 3487-3493, (2007).

11. C. C. Tsai, H. C. Wei, C. H. Hsieh, J. S. Wu, C. E. Lin, C. Chou, “Linear birefrigence parameters determination of a multi-order wave plate via detection of a large oblique incidence angles,” Optics Communications 281, 3036-3041, (2008).

12. S.-M. F. Nee, C.-J. Yu, J.-S. Wu, H.-S. Huang, C. Chou, ”Error analysis of a simple and accurate optical coherent ellipsometer” Physica Status Solidi A 205, 931-935, (2008).

13. S.-M. F. Nee, C.-J. Yu, J.-S. Wu, H.-S. Huang, C.-E. Lin, C. Chou, ”Degrees of polarization and coherence of paired linear polarized laser beam by scattering glass plate measured using optical coherent ellipsometer,” Optics Express 16, 4286-4295, (2008).

14. C.-C. Tsai, H.-C. Wei, S.-L. Huang, C.-E. Lin, C.-J. Yu, C. Chou, “High speed interferometric ellipsometer,” Optics Express 16, 7778-7788, (2008).

15. L.-P. Yu, C. Chou, J.-S. Wu, Y.-H. Chan, “Measurement of diffuse photon-pairs density wave in a multiple-scattering medium,” Applied Optics 47, 2708-2714, (2008). This paper has been selected to The Virtual Journal for Biomedical Optics (VJBO) in vol. 3, issue 6, June 17, (2008).

16. C.-E. Lin, C.-J. Yu, Y.-C. Li, C. Chou, “High sensitivity two-frequency paired polarized interferometer on Faraday rotation angle measurement of ambient air with single traveling configuration,” Journal of Apply Physics 104, 033101, (2008).

17. C. Chou, H.-K. Teng, C.-C. Tsai, J.-S. Wu, “Differential-phase decoder in polarized optical heterodyne interferometer,” Journal of Optical Society of America A 25, 2630-2635, (2008). This paper has been selected to The Virtual Journal for Biomedical Optics (VJBO) in vol. 4, issue 1, (2008).

18. H.-J. Huang, T.-Y. Hsieh, L.-D. Chou, W.-C. Kuo, C. Chou, “Analog differential-phase detection in optical coherence reflectometer,” Optics Express 16, 12847-12858, (2008). This paper has been selected to The Virtual Journal for Biomedical Optics (VJBO) in vol. 3, issue 10, Oct 1, (2008).

19. Y.-C. Li, Y.-F. Chang, L.-C. Su, C. Chou, ”Differential phase surface plasmon resonance biosensor,” Analytical Chemistry 80, 5590-5595, (2008).

20. Y.-F. Chang, R.-C. Chen, Y.-J. Lee, S.-C. Chao, L.-C. Su, Y.-C. Li, C. Chou, “Localized surface plasmon coupled fluorescence fiber-optic biosensor for alpha-fetoprotein detection in human serum,” Biosensors & Bioelectronics 24, 1610-1614, (2009).

21. C.-H. Lin, H.-Y. Chen, C.-J. Yu, P.-L. Lu, C.-H. Hsieh, B.-Y. Hsieh, Y.-F. Chang, C. Chou, “Quantitative measurement of binding kinetics in sandwich assay using a fluorescence detection fiber-optic biosensor,” Analytical Biochemistry 385, 224-228, (2009).

22. C.-J. Yu, C.-E. Lin, L.-C. Su, C. Chou, “Heterodyne linear polarization modulation ellipsometer,” Japanese Journal of Applied Physics 48, 032403, (2009).

23. C.-J. Yu, C.-E. Lin, H.-K. Teng, C.-C. Tsai, C. Chou, “Dual-frequency paired polarization phase shifting ellipsometer,” Optics Communications 282, 1516-1520, (2009).

24. H.-C. Wei, C.-C. Tsai, L.-P. Yu, C.-E. Lin, C.-J. Yu, M.-H. Liu, C. Chou, “Two-dimensional cell parameters of twisted nematic liquid crystal with an amplitude-sensitive heterodyne ellipsometer,” Applied Optics 48, 1628-1634, (2009).

25. C.-J. Yu, C.-E. Lin, L.-P. Yu, C. Chou, “Paired circularly polarized heterodyne ellipsometer,” Applied Optics 48, 758-764, (2009).

26. H.-T. Chien, C.-K. Lee, H.-K. Chiu, K.-C. Hsu, C.-C. Chen, J.-A. A. Ho, C. Chou, “The Comparison Between the Graded Photonic Crystal Coupler and Various Couplers,” Journal of Lightwave Technology 27, 2570-2574, (2009).

27. J. C. Huang, Y.-F. Chang, K.-H. Chen, L.-C. Su, C.-W. Lee, C.-C. Chen, Y.-M. A. Chen, C. Chou, “Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in human serum using a localized surface plasmon coupled fluorescence fiber-optic biosensor,” Biosensor & Bioelectronics 25, 320-325, (2009).

28. C.-E. Lin, J.-G. Chang, L.-D. Chou, C.-J. Yu, C.-C. Lee, C. Chou, “Two-Frequency Paired Polarization Interferometer for Faraday Rotation Angle Detection,” Japanese Journal of Applied Physics 48, 082501, (2009).

29. C.-J. Yu, C.-E. Lin, Y.-C. Li, L.-D. Chou, J.-S. Wu, C.-C. Lee, and C. Chou, “Dual-frequency heterodyne ellipsometer for characterizing generalized elliptically birefringent media,” Optics Express 17, 19213-19224, (2009).

30. C.-E. Lin, C.-J. Yu, C.-L. Chen, L.-D. Chou, C. Chou, “Kinetics of glucose mutarotation using equal-amplitude paired polarized polarimeter,” Journal of Physical Chemistry A 114, 1665-1669, (2010).

31. C.-J. Yu, J.-G. Chang, C.-E. Lin, C.-C. Lee, C. Chou, “Digital circularly polarized heterodyne ellipsometer,” Thin Solid Film 518, 3391-3395, (2010).

32. M.-H. Liu, W.-C. Kuo, H.-C. Wei, C.-C. Tsai, C.-J. Yu, B.-J. Liang, and C. Chou, “Cell parameter measurement of a twisted nematic liquid crystal device using interferometric ellipsometer under normal incidence,” Optics Express 18, 8759-8766, (2010).

33. L.-C. Su, R.-C. Chen, Y.-C. Li, Y.-F. Chang, Y.-J. Lee, C.-C. Lee, C. Chou, “Detection of Prostate-Specific Antigen with a Paired Surface Plasma Wave Biosensor,” Analytical Chemistry 82, 3714-3718, (2010).

34. J.-S. Wu, C.-H. Chang, L.-P. Yu, L.-D. Chou, H.-F. Chang, H.-F. Yau, C.-C. Lee, C. Chou, “Zeeman laser scanning confocal microscope and its ability on reduction of specimen-induced spherical aberration,” Optics Express 18, 13136-13150. (2010).

35. Y.-F. Chang, S.-F. Wang, J. C. Huang,L.-C. Su, L. Yao,Y.-C. Li, S.-C. Wu, Y.-M. A. Chen,J.-P. Hsieh, C. Chou, “Detection of swine-origin influenza A (H1N1) viruses using a localized surface plasmon coupled fluorescence fiber-optic biosensor,” Biosensor & Bioelectronics 26, 1068-1073, (2010).

36. J.-A. A. Ho, H.-C. Chang, N.-Y. Shih, L.-C. Wu, Y.-F. Chang, C.-C. Chen, and C. Chou, “Diagnostic Detection of Human Lung Cancer-Associated Antigen Using a Gold Nanoparticle-Based Electrochemical Immunosensor,” Analytical Chemistry 82, 5944-5950, (2010).

37. C.-Y. Chang, L. Wang, J.-T. Shy, C.-E. Lin, C. Chou, “Sensitive Faraday rotation measurement with auto-balanced photodetection,” Review of Scientific Instruments 82, 063112, (2011).

38. Y.-F. Chang and S.-H. Hung, Y.-J. Lee, R.-C. Chen, L.-C. Su, C.-S. Lai, C. Chou, “Discrimination of breast cancer by measuring prostate-specific antigen levels in women serum,” Analytical Chemistry 83, 5324-5328, (2011).

39. L.-C. Su and Y.-F. Chang, C. Chou, J. A. Ho, Y.-C. Li, L.-D. Chou, C.-C. Lee. “Binding kinetics of biomolecule interaction at ultra-low concentrations based on gold nanoparticle enhancement,” Analytical Chemistry 83, 3290-3296, (2011).

40. N.-C. Chen, W.-C. Lien, C.-R. Liu, Y.-L. Huang, Y.-R. Lin, C. Chou, S.-Y. Chang, C.-W. Ho, “Excitation of surface plasma wave at TiN/air interface in the Kretschmann geometry,” Journal of Applied Physics 109, 043104, (2011).

41. Y.-C. Li, C.-C. Chiou, J.-D. Luo, W.-J. Chen, L.-C. Su, Y.-F. Chang, Y.-S. Chang, C.-S. Lai, C.-C. Lee, C. Chou, “Sensitive detection of unlabeled oligonucleotides using a paired surface plasma waves biosensor,” Biosensor & Bioelectronics 35, 342-348, (2012).

42. L.-C. Su, C.-M. Chang, Y.-L. Tseng, Y.-F. Chang, Y.-C. Li, Y.-S. Chang, C. Chou, “A Rapid and Highly Sensitive Method for Influenza A (H1N1) Virus Detection,” Analytical Chemistry 84, 3914-3920, (2012).

43. C.-J. Yu, Y.-T. Tseng, K.-C. Hsu, and C. Chou, “Full field characterization of a twisted nematic liquid crystal device using equivalence theorem of a unitary optical system,” Applied Optics 51, 238-244, (2012).

44. C.-H. Chao and Y.-F. Chang, H.-C. Chen, L.-Y. Lin, P.-C. Yu, Y.-S. Chang, Y.-J. Lee, and C. Chou, “Detection of urine cofilin-1 from patients hospitalized in the intensive care unit using the metal-enhanced fluorescence technique,” Sensors and Actuators B-Chemical 173, 184-190 (2012).

45. C. Chou, C.-W. Ho, S.-Y. Chang, N.-C. Chen, Y.-F. Chang, L.-C. Su, C.-C. Lee, “Biosensor based on degree of coherence of a pair of surface plasma waves,” The Journal of Physical Chemistry C 116, 25022-25027 (2012).

46. Jheng-Syong Wu, Chien Chou, Ying-Chang Li, Chi-Jen Yu, Chun-Hao Chuang,Li-Ping Yu, Yu-Hsin Chang, and Cheng-Chung Lee, “Two-Dimensional Distributions of Five Cell Parameters of Twisted Nematic Liquid Crystal Device by Numerical Photometric Ellipsometer,” Japanese Journal of Applied Physics 51, 086601(2012)

47. Y.-F. Chang, J.-S. Yu, Y.-T. Chang, S.-Y. Chang, L.-C. Su, C.-C. Wu, Y.-S. Chang, C.-S. Lai, C. Chou, “The utility of a high-throughput scanning biosensor in the detection of the pancreatic cancer marker ULBP2,” Biosensor & Bioelectronics 41, 232-237 (2013).

48. Li-Chen Su, Ya-Chung Tian, Ying-Feng Chang, Chien Chou*, Chao-Sung Lai*, “Rapid detection of urinary polyomavirus BK by heterodyne-based surface plasmon resonance biosensor,” Accepted by Journal of Biomedical Optics (2014)

49. Ying-Feng Chang, Cheng-Han Chao, Lih-Yuan Lin, Cheng-Han Tsai, Chien Chou*, and Yi-Jang Lee*, “Determination of urine cofilin-1 level in acute kidneyinjury using a high-throughput localized surface plasmon-coupled fluorescence biosensor,” Journal of Biomedical Optics 19(1), 011004 (January 2014)

Others Journals:

1. H. F. Chang, C. Chou, H. F. Yau, Y. H. Chan, J. N. Yi, J. S. Wu, “Angular distribution of polarized photon-pairs in a scattering medium with a Zeeman laser scanning confocal microscope” Journal of Microscopy 223, 26-32, (2006).

2. Y.-F. Chang, T.-C. Chang, Y.-M. Huang, K.-W. Yu, B.-Y. Hsieh, Y.-C. Chung, C. Chou, “Fiber Optic Biosensor for the Identification of E. coli in Pure Cultures Isolated from Blood,” Journal of Bionanoscience 1,117-121, (2007).

3. H.-C. Wei, C.-H. Hsieh, C.-C. Tsai, L.-P. Yu, C. Chou, “Determination of linear birefringence of a multiple-order wave plate using a phase-sensitive ellipsometer,” Phys. Stat. Sol. C 5, 1411-1413, (2008).

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